Ipamorelin is a pentapeptide known as a growth hormone secretagogue, meaning it stimulates the release of growth hormone (GH) from the pituitary gland. This selective GH secretagogue is also a ghrelin receptor agonist, which mimics some effects of the hunger hormone ghrelin. Unlike other GH-releasing compounds, Ipamorelin is known for causing fewer side effects because it primarily targets GH without significantly impacting cortisol or prolactin levels, which can lead to fewer side effects such as stress hormone elevation [1].
Ipamorelin is often used in peptide therapy for its anti-aging and body composition benefits, including support for fat loss, increased lean muscle mass, and improved recovery time. Its high GH potency and targeted mechanism make it useful for those looking to enhance muscle growth and fat metabolism. Clinical studies have shown it to be effective both in vitro and in vivo in promoting GH secretion without the adverse effects sometimes associated with other GH-stimulating peptides [2].
- cancer.gov – Definition of ipamorelin
- pubmed.ncbi.nlm.nih.gov – Ipamorelin, the first selective growth hormone secretagogue
- vitalityhrt.com – Ipamorelin Peptide Therapy at the Renew Vitality Clinic
- transformyou.com – All About Ipamorelin
- wikipedia.org – Ipamorelin
- pubmed.ncbi.nlm.nih.gov – Ipamorelin, a new growth-hormone-releasing peptide …